Effects of a water-soluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplets in cultured rat adrenocortical cells. While there are a wide range of reported uses of Cordyceps sinensis in the literature, the reports that extracts of this fungus may alter apoptotic homeostasis are most intriguing. Parcell AC, Smith JM, Schulthies SS, et al. The Benefits of Cordyceps Sinensis & Militaris (& Side Effects) Alongside the potential benefits of Cannabinoids, one of the most exciting ‘up-and-coming’ well-being waves is that of the fungi (or mushrooms). View abstract. J Administration Traditional Chinese Med 1995;13(11):660. Cyclophosphamide (Cytoxan, Neosar) is used to decrease the immune system. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Sun, M., Yang, Y. R., Lu, Y. P., Gao, R., Wang, L., Wang, J., and Tang, K. [Clinical study on application of bailing capsule after renal transplantation]. Follow the dosage advice listed on your cordyceps supplement, or speak with an herbalist about treating a specific condition. View abstract. they fight off infections and provide antioxidant protection, to produce molecules for energy production, cordyceps is used as a stimulant and an adaptogen. While C. sinensis is by far the most valued and studied Cordyceps species, others have also been used for their potential health benefits.Among these, Cordyceps militaris is the most well-known and researched one. These side effects are often temporary and mild. Guan, Y. J., Hu, Z., and Hou, M. [Effect of Cordyceps sinesis on T-lymphocyte subsets in chronic renal failure]. © Therapeutic Research Faculty 2020. Wong, E. L., Sung, R. Y., Leung, T. F., Wong, Y. O., Li, A. M., Cheung, K. L., Wong, C. K., Fok, T. F., and Leung, P. C. Randomized, double-blind, placebo-controlled trial of herbal therapy for children with asthma. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. View abstract. 22 June 2015. The side effects of each fungus are vastly different. Because of its long history in traditional medicine, Cordyceps militaris is often used by natural health practitioners. J Cell Biochem 1998;69:483-9. Save my name, email, and website in this browser for the next time I comment. Sacc. 10 Count (Pack of 1) 4.5 out of 5 stars 8,188. View abstract. Cheng Q. Mei QB, Tao JY, Gao SB, et al. View abstract. Lu, L. [Study on effect of Cordyceps sinensis and artemisinin in preventing recurrence of lupus nephritis]. Transplant.Proc. Zhang, Z. H., Zhang, W. D., and Yao, K. [Treatment of chronic allograft nephropathy with combination of enalapril and bailing capsule]. Chinese J Integrated Traditional Western Med 1993;13(11):660. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. More specifically, cordycepin is known for: Polysaccharides are a type of carbohydrate composed of long chains of monosaccharides. DIABETES. View abstract. These are not your traditional cap and stem mushrooms, the Cordyceps fruiting body is actually known as an ascocarp, but for our purposes, we can just refer to it as a mushroom! Hypoglycemic activity of a polysaccharide (CS-F30) from the cultural mycelium of Cordyceps sinensis and its effect on glucose metabolism in mouse liver. They also boost immune system responses and may improve quality of life for individuals who have a compromised immune system, such as the sick and elderly. However, two specific species are now the focus of detailed research: Cordyceps sinensis and Cordyceps militaris. Stay on the safe side and avoid use. Taken under the tongue, swallowed or injected, some of the therapeutic uses for AMP and ATP include treatment for: Other plant chemicals in C. militaris include ergosterol and mannitol. Biol Pharm Bull 1993;16:1291-3. View abstract. 1985;5:46-47. Complement Ther Med. Journal of Administration of Traditional Chinese Medicine 1995;5(Suppl):14-18. Web. Chen JR, Yen JH, Lin CC, et al. Usage of these fungi is increasing as its proponents cite a host of possible health benefits. Nephrol.Dial.Transplant. 2017;30:84-92. doi: 10.1016/j.ctim.2016.12.007. Han SR. View abstract. 2009;29(11):975-978. Cordyceps militaris, a parasitic fungus, is a valuable source of many phytonutrients (plant chemicals) and is thought to provide an array of therapeutic benefits and support good health. View abstract. Chin Med J (English) 1992;105:97-101. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. View abstract. Cordycepin 3′-deoxyadenosine (C10H13N5O3) is an active constituent of C. militaris and is known to possess a variety of beneficial characteristics. Yang YZ, Wang LS, Deng HY, and et al. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. IL vostro cordyceps quali vantaggi presenta rispetto al cordycep CS-4, I will like to receive more on this drugs via email. Side Effects. Can anyone suggest me, Your email address will not be published. Polysaccharides in fungi. Yoo, H. S., Yoon, J., Lee, G. H., Lee, Y. W., and Cho, C. K. Best case series program supportive cases of Cordyceps militaris- and panax notoginseng-based anticancer herbal formula. [Short-term observation of treating chronic hepatitis B and post-hepatitis cirrhosis with XinGanBao]. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303. Select a condition to view a list of vitamins. Chiu JH, Ju CH, Wu LH, et al. Am J Chin Med 1998;26:159-70. J Altern Complement Med 1998;4:429-57. Cordyceps has been known for centuries in Asian culture as an aphrodisiac. Prednisolone is sometimes used to decrease the immune system. Qu, ZY, Song, K, Cai, WL, and Tang, J. Phytochemistry 1999;51:891-8. Experiences in treating patients with chronic bronchitis and pulmonary diseases with Cs-4 capsule (JinShuiBao). Increased aerobic capacity in healthy elderly human adults given a fermentation product of Cordyceps Cs-4. doi: 10.1002/14651858.CD009698.pub2. Another interesting but less known use of Cordyceps … * Helps Muscles Building and Improves Physical Performance. Che YS and Lin LZ. Tong Y. Common side effects of cordyceps include: Increased symptoms of autoimmune diseases Slow blood clotting (increased risk of bleeding in people with bleeding disorders) Increased risk of bleeding during surgery XXXII. Sacc]. Clinical observations of Jin Shui Bao in the treatment of hyperlipidemia. Treatment of 32 tussive asthma patients with JinShuiBao. Tsuk S, Lev YH, Rotstein A, Zeev A, Carasso R, Steiner G. Effects of a commercial supplement of Ophiocordyceps sinensis and Ganoderma lucidum on physiological responses to maximal exercise in healthy young participants. Clinical observation on therapeutic effects of JinShuiBao on coronary heart disease, hyperlipidemia, and blood rheology. Life threatening or permanent side effects are not usually associated with routine cordyceps supplementation. Zhong.Xi.Yi.Jie.He.Za Zhi. But other early research shows no benefit. Get it as soon as Fri, Apr 23. [Short-term curative effect of cultured Cordyceps sinensis (Berk.) Cordycepin 3′-deoxyadenosine (C10H13N5O3) is an active constituent of C. militarisand is known to possess a variety of beneficial characteristics. A very small group of people may suffer diarrhoea, dry mouth and nausea, but these often pass quickly. American clinicians and physicians use adenosine and its derivatives for a variety of medical purposes. New York, NY: The Haworth Herbal Press, 1999. 5) Enhances cellular oxygen intake. Cordyceps is actually a genus of mushrooms, and the term has been used to refer to a number of different species- most commonly Cordyceps sinensis and Cordyceps militaris. Front Biosci (Elite.Ed) 2011;3:301-307. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Health News and Information, Delivered to Your Inbox, Vitamins and Supplements to Avoid with Hepatitis C. Quiz: What Do You Know About Vitamin B12 Deficiency? Balon, T. W., Jasman, A. P., and Zhu, J. S. A fermentation product of Cordyceps sinensis increases whole-body insulin sensitivity in rats. In China, Cordyceps has been approved as a safe, natural drug, and it is already in use in hospitals there. Life Sci 9-5-2003;73(16):2127-2136. Don't take cordyceps if you have cancer, diabetes There are no known side effects to taking Cordyceps, although experts warn that more tests are needed before they can say that it is completely safe to take. Yoshida J, Takamura S, Yamaguchi N, et al. Ding, C., Tian, P. X., Xue, W., Ding, X., Yan, H., Pan, X., Feng, X., Xiang, H., Hou, J., and Tian, X. Efficacy of Cordyceps sinensis in long term treatment of renal transplant patients. Enhances Sex Drive. All rights reserved. View abstract. Other have reported a lingering metallic taste after using a cordyceps product, which may take longer to resolve. Required fields are marked *. The term cordyceps is now used to refer to any number of species taken as a dietary supplement. Chung Hua I Hsueh Tsa Chih (Taipei) 1992;72:27-9, 63. Kai Z, Yongjian L, Sheng G, Yu L. Effect of Dongchongxiacao (Cordyceps) therapy on contrast-induced nephropathy in patients with type 2 diabetes and renal insufficiency undergoing coronary angiography. 2008;28(9):806-809. Wild Cordyceps sinensis comes from a caterpillar and fungus combination, and is rare, extremely expensive and not available as a dietary supplement. Chen YJ, Shiao MS, Lee SS, Wang SY. Negative side effects may include diarrhea, dry mouth and upset stomach. Li, Y., Xue, W. J., Tian, P. X., Ding, X. M., Yan, H., Pan, X. M., and Feng, X. S. Clinical application of Cordyceps sinensis on immunosuppressive therapy in renal transplantation. Wan F, Guo Y, and Deng X. J Administration Traditional Chinese Med 1995;5(suppl):23-24. Today, the supplement is in demand throughout Asia, Europe, South America and North America for its purported health benefits. 2014;(12):CD008353. J Tradit Chin Med. View abstract. 3) It provides anti-anging and fatigue-reducing effects. Medicine and Science in Sports and Exercise 1999;31(Suppl):S174. Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others. 2018;20(4):359-367. Ren Fail. I’m curious why one study from Department of Pharmacy, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu 210036, China, Received 29 October 2012; Revised 8 January 2013; Accepted 16 January 22012 stated “We conclude that dietary contamination with C. militaris may have renal toxicity potentials, at least in part by causing oxidative damage to the kidney.”, There’s a discussion about this here: https://www.longecity.org/forum/topic/99189-cordyceps-militaris-rat-study-finds-unexpected-nephrotoxicity/, How we sell online cordyceps military? Wang, N. Q., Jiang, L. D., Zhang, X. M., and Li, Z. X. Longrich Cordyceps coffee is a special blend of cordyceps militaris and coffee beans, specially formulated to improve health. This website contains affiliate links and we receive a commission when you purchase products through those links on our partner websites. Zhu, J. L. and Liu, C. [Modulating effects of extractum semen Persicae and cultivated Cordyceps hyphae on immuno-dysfunction of inpatients with posthepatitic cirrhosis]. Antitumor activity of an extract of Cordyceps sinensis (Berk.) Growth inhibitors against tumor cells in Cordyceps sinensis other than cordycepin and polysaccharides. It stresses the fact that Cordyceps Militaris is a natural extract without any side effects. Chung Kuo Chung Yao Tsa Chih 1989;14:616-8, 640. Inhibitory effect of Cordyceps sinensis on spontaneous liver metastasis of Lewis lung carcinoma and B16 melanoma cells in syngeneic mice. Cheng JH, Guo XM, and Wang X. 2) It improves physical performance. Cordyceps Sinensis vs. Cordyceps Militaris. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454. Int J Med Mushrooms. J Altern.Complement Med 2009;15(10):1091-1097. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 1992;12:267-9, 259. [Effect of cordyceps sinensis on cellular immunity in rats with chronic renal insufficiency]. Kuo YC, Tsai WJ, Shiao MS, et al. Cordyceps sinensis as an immunomodulatory agent. Chen, S., Li, Z., Krochmal, R., Abrazado, M., Kim, W., and Cooper, C. B. Zhongguo Zhong.Yao Za Zhi. 2009;41(5):1565-1569. "Traditional Uses and Medicinal Potential of Cordyceps Sinensis of Sikkim." Bok JW, Lermer L, Chilton J, et al. View abstract. View abstract. Cordyceps dosage depends on the reason they are being used, but most studies in humans have used 1,000–3,000 milligrams per day, which doesn’t seem to be associated with any common side effects. J Altern Complement Med 2002;8(3):315-323. View abstract. [Antiarrhythmic effects of Cordyceps sinensis (Berk.) Reishi Mushrooms have less severe reported side effects. Research of Chinese Materia Medica 1994;1:19-20. Int J Med Mushrooms. Cordyceps sinensis- and Rhodiola rosea-based supplementation in male cyclists and its effect on muscle tissue oxygen saturation. Panda, Ashok Kumar, and Kailash Chandra Swain. Some early research shows that taking cordyceps while undergoing an exam using contrast dye reduces the chance of kidney damage caused by the dye. 1) It enhances and strengthens the immune system. There are approximately 400 different cordyceps species. Researchers hypothesized that it has a positive effect on reducing the negative effects of stress and improving sex hormone production. Chronic kidney disease is a global health problem that is very hard to treat, costs the healthcare system billions of… View abstract. I haven’t come across any studies on individuals using Cordyceps Militaris with Graves’ Disease, but here is the link to a study on the use of Corbrin Capsule (CS-C-Q80) which is a drug derived from Cordyceps sinensis extract: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045992/. Pregnant women, new moms, surgery patients, diabetics and those with liver and/or kidney disease should not supplement with Cordyceps militaris without clearly understood permission from their primary caregivers. Longrich Cordyceps Coffee is a special blend of cordyceps militaris and coffee beans, specially formulated to improve health. Chin Med J (English) 1991;104:4-8. Symptoms typically resolve once the treatment is stopped. View abstract. 2004;36(3):504-509. 4) Improves respiratory functions. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 1996;16:733-7. This compound has a very potent anti-cancer, anti-oxidant and anti-inflammatory activity. Cochrane Database Syst Rev. Chen GZ, Chen GL, Sun T, et al. [Effect of Jinshuibao capsule on the immunological function of 36 patients with advanced cancer]. 2015;(10):CD009698. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Having antimicrobial, anticancer, antimetastatic, insecticidal and immunomodulatory properties; Slowing down the aggregation of platelets; Limiting cellular invasiveness/migration; Reducing tumor development and progression; Cachexia and weight loss associated with cancer; Decrease triglycerides and LDL cholesterol; Induce vasodilation, thereby improving circulation; Diminish kidney damage caused by immunosuppressant drugs, such as cyclosporine; Delay further decline in damaged kidneys; Loosen phlegm, which helps in the treatment of bronchitis, asthma and other breathing conditions; Improve tolerance of chemotherapy and radiation; Increase sex drive and help support the treatment of ED (erectile dysfunction) symptoms. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). 1) It enhances and strengthens the immune system. 2) It improves physical performance. View abstract. Cheng, YP, Liu, WZ, Shen, LM, and Xu, SN. View abstract. Zhao K, Li Y, Zhang H. Role of Dongchongxiacao (Cordyceps) in prevention of contrast-induced nephropathy in patients with stable angina pectoris. Kidney damage caused by contrast dyes (contrast induced nephropathy). Keep in mind that natural products are not always necessarily safe and dosages can be important. Cordyceps sinensis (CordyMax Cs-4) supplementation does not improve endurance exercise performance. [Effect of fuzheng huayu recipe in treating posthepatitic cirrhosis]. Chinese Traditional Patented Med 1988;9:29-31. Further, they fight off infections and provide antioxidant protection against free radical damage. Xiao, Y, Huang, XZ, Cheng, G, and et al. Cordyceps Militaris vs. Diabetes. 1995;10(1):142-143. Cordyceps seems to increase the immune system. View abstract. Shao, G. [Treatment of hyperlipidemia with cultivated Cordyceps--a double-blind, randomized placebo control trial]. [Experimental study on effect of Cordyceps sinensis in ameliorating aminoglycoside induced nephrotoxicity]. Zhou L, Yang W, Xu Y, et al. J Tradit Chin Med. Dai, G., Bao, T., Xu, C., Cooper, R., and Zhu, J. S. CordyMax Cs-4 improves steady-state bioenergy status in mouse liver. Liu C, Lu S, Ji MR. [Effects of Cordyceps sinensis (CS) on in vitro natural killer cells]. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. Sacc. 1985;5(11):652-4, 642. Cordyceps is considered safe for short-term use. Adenosine contained in Cordyceps militaris combines with phosphates to produce molecules for energy production, such as AMP (adenosine monophosphate) and ATP (adenosine triphosphate). Those who wish to lose some weight will find be happy to learn more about the connection between Cordyceps Militaris and Nephrol Dial Transplant 1995;10:142-3. Learn more about cordyceps health benefits, nutrition facts, dosage, side effects and warnings. Treating Infertility & Dysfunction The ability of Cordyceps to stimulate the production of Oestrogen in the body is drawing attention of leading specialists treating female infertility. View abstract. It may also have activity against cancer cells and may shrink tumor size, particularly with, The appropriate dose of cordyceps depends on several factors such as the user's age, health, and several other conditions. Cordyceps is a botanical genus that is comprised of hundreds of species, all of which are parasitic. Xu RH, Peng XE, Chen GZ, Chen GL. C. militaris contains beta-glucan polysaccharides, which are known to reduce LDL and total cholesterol levels. View abstract. View abstract. View abstract. Chinese Traditional Herbal Drugs 1986;17(6):256-258. View abstract. Kiho T, Yamane A, Hui J, et al. J Administration Traditional Chinese Med 1995;5(suppl):7-8. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Quio, YL and Ma, XC. Research shows that Cordyceps Militaris has similar benefits to the traditional wild Cordyceps Sinensis. Yang W, Deng X, and Hu W. Clinical study of fermentation product of Cordyceps sinensis on treatment of hyposexuality. Colson SN, Wyatt FB, Johnston DL, et al. Despite their longstanding popularity and use, few clinical trials have been conducted on either C. sinensis or C. militaris, and no … 2007;32(15):1566-1568. C. militaris is cultivated on substrates free from insects in a sustainable manner. View abstract. Cordyceps Side Effects. View abstract. Zhang Z, Huang W, Liao S, and et al. C. militaris may act in many ways to support good health. The cordyceps mushroom has been a staple of Chinese medicine for millennia. The aim of this study is to determine the efficacy of C. militaris for enhancing … OTHER NAME(S): Caterpillar Fungus, Caterpillar Mushroom, Cs-4, Champignon Chenille, Chinese Caterpillar Fungus, Cordyceps sinensis, Dong Chong Xia Cao, Dong Chong Zia Cao, Hsia Ts'Ao Tung Ch'Ung, Jinshuibao Jiaonang, Jinshuibao Pian, Ophiocordyceps sinensis, Tochukaso, Vegetable Caterpillar. In particular, the chemical is being investigated for its use in cancer treatment, but studies are still in the early stages. Cordyceps has been observed to exhibit immunomodulating properties and it is not recommended for use in conjunction with prescription or over-the-counter medications that target the immune system. [Effect of dongchong xiacao capsule on airway inflammation of asthmatic patients]. Taking cordyceps along with cyclophosphamide (Cytoxan, Neosar) might decrease the effectiveness of cyclophosphamide (Cytoxan, Neosar). View abstract. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. View abstract. 2013;33(3):283-286. Biol Pharm Bull 1996;19:294-6. In animal tests, cordyceps has been observed to: Although animal studies have yielded some positive results, research into the health benefits of Cordyceps militaris is still in its infancy and the fungus is not used within the Western medical tradition. 1992;12(6):338-9, 323. View abstract. [Clinical and laboratory studies of JinShuiBao (Cs-4) in scavenging oxygen free radicals in elderly senescent XuZheng patients]. Paterson RR. Jpn J Exp Med 1989;59:157-61. This video is all about how we grow cordyceps militaris organically and commercially. J Strength Cond Res 2005;19:358-63. View abstract. Natural cordyceps is hard to get and may be expensive. However, the anti-cancer effects of cordyceps extend beyond stopping cancer growth. Xu F, Huang JB, Jiang L, et al. Cordyceps is a fungus that lives on certain caterpillars in the high mountain regions of China. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Your email address will not be published. and Cephalosporium sinensis Chen sp. The artificial cultivation of medicinal Caterpillar Fungus, Ophiocordycepssinensis (Ascomycetes): a review. Effects of cordyceps sinensis on natural killer activity and colony formation of B16 melanoma. Yamaguchi N, Yoshida J, Ren LJ, et al. View abstract. Zhou DH, Lin LZ. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Moreover, it is extremely difficult to find an herbal extract that works for everyone. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. [Sex hormone-like effects of JinShuiBao [Cs-4] capsule: pharmacological and clinical studies]. Cordyceps have been found to lower blood glucose levels and increase blood serum levels, however the mechanism remains unknown. Luo Y, Yang SK, Zhou X, Wang M, Tang D, Liu FY, Sun L, Xiao L. Use of Ophiocordyceps sinensis (syn. These effects center around possible allergies instead of life-threatening possibilities. View abstract. Kiho T, Hui J, Yamane A, Ukai S. Polysaccharides in fungi. Cordyceps might increase the immune system. Research demonstrates that Cordyceps militaris has similar actions to the rare version and can be substituted for clinical applications. Am J Chin Med 1996;24:111-25. View abstract. View abstract. Zhao Y. against murine tumor cell lines. 6-28-2000;25(3):248-250.